HPE expands AI server range with NVIDIA Blackwell GPU solutions
Hewlett Packard Enterprise has introduced several updates to its NVIDIA AI Computing by HPE portfolio, aimed at supporting enterprise clients seeking to accelerate agentic and physical AI deployment across a variety of use cases.
Server advancements
Among the headline updates, HPE has confirmed it will ship new HPE ProLiant Compute servers equipped with NVIDIA RTX PRO 6000 Blackwell Server Edition GPUs. This includes a new 2U RTX PRO Server form factor in the DL385 Gen11 model, as well as an 8-GPU 4U configuration with the DL380a Gen12 model. According to HPE, the DL385 Gen11 supports up to two of the Blackwell Server Edition GPUs, providing an air-cooled solution suitable for datacentres coping with increasing artificial intelligence workloads. Meanwhile, the DL380a Gen12 can accommodate up to eight GPUs in a larger form factor, with shipments scheduled to begin in September 2025.
HPE highlighted that the ProLiant Compute servers are purpose-built for handling a variety of tasks, including generative and agentic AI, robotics, industrial automation, visual computing, simulation, 3D modelling, digital twins, and autonomous systems. Security features on the Gen12 models include HPE Integrated Lights Out 7 Silicon Root of Trust and a secure enclave for tamper-resistant protection and quantum-resistant firmware signing.
The company states that its server management platform, HPE Compute Ops Management, can reduce IT hours spent on server management by up to 75% and lower downtime by an average of 4.8 hours per server annually. HPE has also indicated that these servers are designed to be flexible and scalable, able to support a growing range of GPU-accelerated workloads across the enterprise.
AI development platform
HPE Private Cloud AI, a collaborative development with NVIDIA, will incorporate support for the latest NVIDIA AI models. This includes the NVIDIA Nemotron agentic AI model, Cosmos Reason vision language model for robotics and physical AI, and the NVIDIA Blueprint for Video Search and Summarization (VSS 2.4). These additions will allow customers to build and deploy video analytics AI agents that can process extensive volumes of video data and extract actionable insights. The new release promises seamless scalability across GPU generations, air-gapped management, and enterprise multi-tenancy.
Continuous integration with NVIDIA technologies will also allow HPE Private Cloud AI to deliver rapid deployment of NVIDIA NIM microservices, with access provided via HPE AI Essentials. The platform is positioned to help enterprises handle increasing AI inferencing workloads while retaining control over their data, supporting high performance and security requirements in demanding sectors.
Regional and industry response
"Asia Pacific is one of the fastest-growing AI markets, and enterprises face the imperative to transform ambition into results, with agility and security at the core," said Joseph Yang, General Manager, HPC, AI & NonStop, at HPE APAC and India. "With NVIDIA Blackwell GPUs in our HPE ProLiant servers and the latest NVIDIA AI models in HPE Private Cloud AI, we're enabling customers across APAC to accelerate agentic and physical AI, powering everything from advanced manufacturing to smart cities, while safeguarding data sovereignty and maximizing operational efficiency."
Data sovereignty and operational efficiency were also cited as important capabilities for regional customers working in sectors such as advanced manufacturing and public infrastructure.
"HPE is committed to empowering enterprises with the tools they need to succeed in the age of AI," said Cheri Williams, Senior Vice President and General Manager for Private Cloud and Flex Solutions at HPE. "Our collaboration with NVIDIA continues to push the boundaries of innovation, delivering solutions that unlock the value of generative, agentic and physical AI while addressing the unique demands of enterprise workloads. With the combination of HPE ProLiant servers and expanded capabilities in HPE Private Cloud AI, we're enabling organizations to embrace the future of AI with confidence and agility."
The collaboration between HPE and NVIDIA is expected to support customers managing large-scale enterprise AI workloads, with the infrastructure designed to be as flexible and scalable as present and emerging tasks require.
"Enterprises need flexible, efficient infrastructure to keep pace with the demands of modern AI," said Justin Boitano, Vice President of Enterprise AI at NVIDIA. "With NVIDIA RTX PRO 6000 Blackwell GPUs in HPE's 2U ProLiant servers, enterprises can accelerate virtually every workload on a single, unified, enterprise-ready platform."
Availability
The HPE ProLiant DL385 Gen11 and DL380a Gen12 servers equipped with NVIDIA RTX PRO 6000 Blackwell Server Edition GPUs are currently open for orders, with first shipments expected from September 2025. HPE intends to roll out support for the newest NVIDIA AI models, the Cosmos Reason VLM, and the VSS 2.4 blueprint in HPE Private Cloud AI during the latter half of 2025. The next generation of HPE Private Cloud AI, with Blackwell GPU support, is also slated for release in the same period.
